No, not really, for the same reason .us never caught on in the US. .com was the establised norm, just like .co.uk is the established norm in the UK. I think the jury's still out on whether the new gtld's will have sustained longevity as a desired namespace. I've no doubt people are going to jump on them in the same way they jumped on .us .co. etc etc. It will take years (probably five) for .uk to be the established norm in the UK. Granted, there might be marginal interest from an international audience, but the way it stands the 99.9% of people who will really benefit from this are domainers. I fail to see how businesses that use the .co.uk namespace will see any added benefit. I think as far as business opportunities go, it will only increase the value of good unused .co.uk's because of the namespace legacy. In the future no company worth their salt would be satisfied owning one or the other, they'll want both, whether that's to protect against brand contamination or for vanity's sake. We all know the domains as a pair (.co.uk & .uk) will be worth way more than an extra fiver.