Take profits at specific price points and stick to it. Clear all outstanding debts, mortgages etc. If you have a s&s pension etc, use that as your long term gamble which you can't withdraw money from.
There are people who literally believe that bitcoin is going to become the next currency, that fiat will die, and therefore they think that converting bitcoin to cash is the opposite to banking.... its sad, but there will be people lose literally everything to bitcoin if it pops.